Doxycycline hydrochloride (doxycycline) is the most sensitive and safe broad-spectrum antibacterial, antimycoplasma and chlamydia drug in veterinary medicine. It is effective in the clinical treatment of livestock and poultry diseases, especially in the treatment of bacterial, mycoplasma and viral respiratory diseases of livestock and poultry
Doxycycline hydrochloride (doxycycline) is the most sensitive and safe broad-spectrum antibacterial, antimycoplasma and chlamydia drug in veterinary medicine. It is effective in the clinical treatment of livestock and poultry diseases, especially in the treatment of bacterial, mycoplasma and viral respiratory diseases of livestock and poultry, and has a unique clinical therapeutic value and outstanding effect of prescription application.
From another point of view, it can be seen that doxycycline hydrochloride is popular among veterinarians and farmers in clinical treatment, not to mention many successful treatment cases in veterinary clinic. Just look at the continuous rise of raw material price of doxycycline hydrochloride in recent years, and the use of doxycycline hydrochloride ranks the top three in livestock and poultry breeding every year.
Functional advantage
After contact with sensitive bacteria in vivo, doxycycline hydrochloride can irreversibly bind to the 30S subunit of the ribosome of the sensitive bacteria, thus inhibiting the synthesis of bacterial protein, causing bacterial reproduction and growth to be blocked, reflecting significant bacteriostatic effect. In addition, doxycycline hydrochloride can also act on the cell membrane of bacteria, which can increase the permeability of the bacterial cell membrane and allow the leakage of nucleotides and other important life substances in the bacterial cell, which can inhibit the replication of bacterial DNA and produce antibacterial effect.
Antibacterial characteristics
Doxycycline hydrochloride in the treatment of the effective antibacterial spectrum is relatively wide, it in addition to our clinical common Escherichia coli, Salmonella and Pasteurella and other effective, but also to the poultry balloon inflammation in recent years caused by mycoplasma, chlamydia and avian tracheitis and other infections, also has the exact therapeutic effect. There is for so many years of poultry industry more difficult to control chicken glandular myogastritis pathogens, such as spirochaetes infection, gram-positive and gram-negative aerobic, anaerobic bacterial infection, including some protozoa parasitic diseases have a good drug treatment effect.
Clinical use
Doxycycline hydrochloride is often used in the treatment of avian mycoplasma and swine respiratory diseases, especially for mycoplasma mixed with bacteria treatment effect is also very good.
Bacterial disease, respiratory tract, such as pleuropneumonia, swine lung disease and other diseases, doxycycline + flufenicol + fever-reducing drug effect is good;
Actinomyces, that is, pigs can grow up in various positions of the pus, in addition to streptococcus pyogenes, there is another situation is caused by actinomyces, generally doxycycline effect is better;
Common "body" diseases; Mycoplasma is panting disease, doxycycline + flufenicol (mycoplasma net) effect is good;
Chlamydia, the first is sow abortion, fetal pearl-like to consider, with doxycycline treatment effect is better; The second kind of conjunctivitis, eye red use of tetracycline drugs eye drops eye effect is better;
Spirochaeta (porcine dysentery, etc.), rickettsia used less, not much to say;
Oxytetracycline is generally used for prophylaxis and treatment of sows with less harm and more moderate effects; Doxycycline is commonly found in nursing piglets after seven days, yellow with white, white with gray feces; Fat pigs in the dog days of summer, often have a fever rebound, repeated.
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